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The Hsp104 structure, different modes of translocation, and sequential ...
Hsp104 is a Bifunctional disaggregase. Disaggregation of disordered ...
Hsp104 disaggregation mechanism and features of potentiated variants ...
Operational Plasticity Enables Hsp104 to Disaggregate Diverse Amyloid ...
CryoEM structure of Hsp104 and its mechanistic implication for protein ...
Design principles to tailor Hsp104 therapeutics: Cell Reports
Hsp104 N‐terminal domain interaction with substrates plays a regulatory ...
Hsp104 Gives Clients the Individual Attention They Need: Cell
Yeast HSP78 and HSP104 share a unique regulatory architecture. (A) A ...
Over‐expression of the molecular chaperone Hsp104 in Saccharomyces ...
The Hsp104 N-Terminal Domain Enables Disaggregase Plasticity and ...
A Functional Hsp104 NTD is required for yeast thermotolerance in vivo ...
Overexpression of Hsp104 by Causing Dissolution of the Prion Seeds ...
Tuning Hsp104 specificity to selectively detoxify α-synuclein ...
Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ...
Hsp104 is induced in response to elevated temperature and stationary ...
Structural and mechanistic insights into Hsp104 function revealed by ...
Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor | PNAS
Potentiated Hsp104 Variants Antagonize Diverse Proteotoxic Misfolding ...
Hsp104 - Wikipedia
Substoichiometric Hsp104 regulates the genesis and persistence of self ...
The N domain of Hsp104 mediates binding to NM-YFP fibers and enables ...
Mapping Hsp104 interactions using cross‐linking mass spectrometry ...
The Hsp104 N domain affects protein disaggregation when present. (a ...
Hsp104 NBD1 Variants Suppress TDP-43 Toxicity, Aggregation, and ...
Effect of Hsp104 expression on yeast prion propagation. Pink diamonds ...
Reintroduction of Hsp104 in hsp104-deleted cells restores the shape of ...
Role of Hsp104 in Sup35 prion propagation | Download Scientific Diagram
Mechanistic Insights into Hsp104 Potentiation* - Journal of Biological ...
The Cytoplasmic Chaperone Hsp104 Is Required for Conformational Repair ...
Hsp104 variants and their properties | Download Table
Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase
Protein remodeling by Hsp104. a Hsp104 collaborates with Hsp70 and ...
Hsp104 disaggregase at normal levels cures many [PSI+] prion variants ...
Biochemical properties of the Hsp104 variants. A, shown is ATPase ...
Hsp104 -RYD is a potentiated variant. A, Hsp104 -RYD antagonizes ...
Drivers of Hsp104 potentiation revealed by scanning mutagenesis of the ...
Thermotolerance of Hsp104 (D184S) mutant is not inhibited by GuHCl ...
Structure and function of the molecular chaperone Hsp104 from yeast ...
Split conformation of Chaetomium thermophilum Hsp104 disaggregase ...
Summary of methodology and major findings. Hsp104 monomer and hexamer ...
| ClpB and Hsp104 exhibit specificity for substrate in unfolding ...
Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes ...
Effects of Ssa1 and Hsp104 on temperature tolerance of yeast cells ...
Structure of Calcarisporiella thermophila Hsp104 Disaggregase that ...
CAP caused the aggregation of Hsp104 in the cytoplasm. Yeast cells ...
Hsp104 regions that predominantly form crosslinks. All crosslink ...
Figure 2 from Applying Hsp104 to protein-misfolding disorders ...
Substrate binding by Hsp104. Cryo-EM structures of (A) Hsp104 bound to ...
Redistribution of Hsp104 in response to heat shock. The subcellular ...
Positions of Key Residues in the Hsp104 Hexamer Model Two Hsp104 ...
Hsp104 binding to peptide arrays. A, the primary sequence elements of ...
Hsp104 and ClpB: protein disaggregating machines: Trends in Biochemical ...
Protein abundance for strains with heterozygous disruptions of HSP104 ...
Hsp104 in Closed, Extended, and Open Ring Conformation (A and B ...
Hsp104 Y507A is a hypomorph with altered intrinsic disaggregase ...
Spiraling in Control: Structures and Mechanisms of the Hsp104 ...
Regulation of the Hsp104 Middle Domain Activity Is Critical for Yeast ...
Hsp104 Drives “Protein-Only” Positive Selection of Sup35 Prion Strains ...
The Hsp104 (D184S) mutant possesses lower ATPase and disaggregating ...
Analysis of the toxicity of the HSP104 mutants. A, shown are drop-tests ...
Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of ...
Figure 1 from Potentiated Hsp104 variants suppress toxicity of diverse ...
Functional analysis of engineered Hsp104 Strep-tag variants. (A ...
Hsp104纯化，蛋白质Disaggregase
Motility and Segregation of Hsp104-Associated Protein Aggregates in ...
Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum ...
Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of ...
Frontiers | The yeast molecular chaperone, Hsp104, influences ...
Sp_Hsp104 is required for thermotolerance in S. pombe . (A) The ...
Hsp104, Hsp70, and Hsp40: Cell
Hsp104-K480C and Hsp104-Y507D are toxic at high temperatures. hsp104D ...
Heat shock protein 104 (Hsp104)-mediated curing of [PSI+] yeast prions ...
Subunit interactions influence the biochemical and biological ...
A conserved strategy for structure change and energy transduction in ...
Crystal structure of Hsp104. (A) Overview of ATPase, GFP unfolding, and ...
Inhibitory function of the MD. (A) Ribbon presentation of a modeled ...
Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism ...
-Hsp104 structure and location of mutations that improve [PSI 1 ...
Evidence for an Unfolding/Threading Mechanism for Protein ...
| M-domains control ClpB/Hsp104 activity and Hsp70 cooperation. (A ...
The ClpB/Hsp104 M domain mediates Hsp70-dependent targeting to protein ...
Shorter Lab: Research
Solid-to-liquid phase transition in the dissolution of cytosolic ...
Structural and kinetic basis for the regulation and potentiation of ...
Formation of Hsp104-Positive Aggregates following Heat Shock Requires ...
The disaggregase activity of Hsp104. A, normalized ThT fluorescence ...
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