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Schematic representation of the key enzymatic function of IDH1 and IDH1 ...
Proposed model of mutant IDH1 function in chondrosarcoma cells ...
Comparison of the function of the IDH1 enzyme (wild-type) and its ...
IDH1 Function Supports the Activity of α -KG-Dependent Dioxygenases In ...
Inhibition of IDH1 R132H function in vivo results in an enhanced IFNɣ ...
Compensation for wild-type IDH1 loss of function in GBM tumors ...
IDH1 supports mitochondrial function under nutrient withdrawal in ...
HIF-1α contributes to the tumorigenic function of IDH1 mutation in ...
Effect of IDH1 substrate α-KG on the biological function of RCC cell ...
IDH1 mutations result in both loss and gain of enzyme function ...
Implications of Concurrent IDH1 and IDH2 Mutations on Survival in ...
IDH1 Targeting as a New Potential Option for Intrahepatic ...
Gene of the month: IDH1 | Journal of Clinical Pathology
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted ...
IDH1 is a cytosolic protein with enzymatic activity. A point mutation ...
The IDH1 R132 mutant is shown as an example to illustrate how a ...
Clinical development of IDH1 inhibitors for cancer therapy - Cancer ...
The role of IDHs. IDH1 is located in the cytosol and the peroxisomes ...
IDH1 and IDH2: Not Your Typical Oncogenes: Cancer Cell
Full article: The Roles of IDH1 in Tumor Metabolism and Immunity
LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to ...
Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2 ...
Overexpression of IDH1 constructs in U87 cells. Protein expression ...
IDH1-mediated metabolic reprogramming. In general, IDH1 mutation ...
IDH1 mutation is sufficient to establish the glioma hypermethylator ...
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a ...
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis
Phosphorylation of IDH1 Facilitates Progestin Resistance in Endometrial ...
(A) Illustration of isocitrate dehydrogenase (IDH) function change with ...
FOXOs mediated regulation of IDH1. IDH1 is directly regulated by FOXO ...
Expression of IDH1 R132H alters metabolism in the TCA cycle in U87 ...
IDH1 mutations in five head and neck cancer studies (cBioPortal). A ...
Crotonylation of IDH1 alleviates MASLD progression by enhancing the TCA ...
IDH1 deficiency attenuates gluconeogenesis in mouse liver by impairing ...
Energy Metabolism in IDH1 Wild-Type and IDH1-Mutated Glioblastoma Stem ...
IDH1 treatment increases multimer binding and cytokine production in ...
IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and ...
IDH1 regulates human erythropoiesis by eliciting chromatin state ...
Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic ...
Novel IDH1 Targeted Glioma Therapies - PMC
IDH1 and IDH2 inhibitors | Cancer Biology
Frontiers | Differential metabolic alterations in IDH1 mutant vs ...
MetaMapp- visualizing metabolomics networks: Effect of IDH1 mutations ...
| IDH1 promoted cell migration and invasion and IDH1 knockout decreased ...
IDH1 and IDH2 Mutations as Novel Therapeutic Targets in Acute Myeloid ...
Wild-type IDH1 inhibition enhances chemotherapy response in melanoma - PMC
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular ...
Schematic representation of IDH1 and IDH2 mutations determining the ...
Metabolic adaptations in cancers expressing isocitrate dehydrogenase ...
Frontiers | IDH1: Linking Metabolism and Epigenetics
Overview of IDH1's biological role in normal cellular functions and the ...
Metabolic reprogramming in IDH1-mutated glioma. Acquisition of IDH ...
Krebs cycle to DNA methylation. IDH1/2 wild-type enzymes convert ...
IDH Inhibitors and Immunotherapy for Biliary Tract Cancer: A Marriage ...
Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations ...
IDH mutations in cancer and progress toward development of targeted ...
Figures
(PDF) In silico gene expression analysis reveals glycolysis and acetate ...
Roles of IDH1/2 and TET2 mutations in myeloid disorders | SpringerLink
Gliomas
Targeting Cancer Metabolism
Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular ...
An example of gain-of-function mutation. Most of the gene mutations ...
Clinical Implications of Isocitrate Dehydrogenase Mutations and ...
Isocitrate dehydrogenase/IDH1 Protein Overview | Sino Biological
Isocitrate dehydrogenase mutations in hereditary diseaes | PPTX
Frontiers | Biological Roles and Therapeutic Applications of IDH2 ...
Wild-Type Isocitrate Dehydrogenase-Dependent Oxidative Decarboxylation ...
Catalytic functions of the wild-type and mutated IDH1/IDH2 enzymes. In ...
Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells: Cell
Figure 1.
The Distribution and Significance of IDH Mutations in Gliomas | IntechOpen
Mutant IDH in Gliomas: Role in Cancer and Treatment Options
Figure 1 from IDH mutations in glioma and acute myeloid leukemia ...
(PDF) IDH1: Linking Metabolism and Epigenetics
Characterization of IDH1-mutant-induced gene expression... | Download ...
IDH-Mutant Gliomas | IntechOpen
Chromosomal location and expression characteristics of IDH1-AS1 and ...
Mutant IDH inhibitors induce lineage differentiation in IDH-mutant ...
Molecular Medicine Reports
Frontiers | IDH-mutant gliomas in children and adolescents - from ...
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic ...
Research timeline of cancer energy metabolism reprogramming and IDH1/2 ...
Proteomic Analysis Uncovers Enhanced Inflammatory Phenotype and ...
Coagulation-associated genes according to IDH1/2 status in gliomas ...
New Developments in the Pathogenesis and Therapeutic Targeting of the ...
Consequences of IDH1/2 Mutations in Gliomas and an Assessment of ...
Surgical Neurology International
IDH Mutations in Glioma - IDH Learn More
Functional implication of IDH1/2 mutations in central neuron ...
Isocitrate Dehydrogenase Mutations in Human Cancers: Physiopathologic ...
Recent findings on molecular alterations in IDH1, TP53, and CASP9 in ...
Wild-Type IDH Enzymes as Actionable Targets for Cancer Therapy
Enzyme activity of IDH1/2 wildtype and IDH1/2 mutant. IDH1/2 catalyzes ...
Contribution of metabolic abnormalities to acute myeloid leukemia ...
Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML ...
Frontiers | Genetics and Epigenetics of Glioblastoma: Applications and ...
From genomics to the clinic: biological and translational insights of ...
