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(A). Cells expressing IRF3 GFP and Npro cherry i) Control cells (CON ...
Effect of siRNA-IFN-α on IRF3 and GFP expression. IRF3 (a) and GFP (b ...
Cytoplasmic to nuclear translocation of fish IRF3 by poly-IC and rIFN ...
A key transcription factor for innate immunity: IRF3 | Experimental ...
DBD, IAD and IDR are necessary for IRF3 LLPS a, Representative ...
SIRT1 is required for IRF3 LLPS and innate antiviral immune ...
IRF3 localizes to reovirus viral factories. (A) A549 cells expressing ...
IRF3 is an important molecule in the UII/UT system and mediates immune ...
The viral factory protein μNS sequesters IRF3 reducing antiviral innate ...
aMPV P protein targets IRF3 for inhibiting IFN-b activation in HEK-293T ...
IRF3 Signaling Pathway | BioRender Science Templates
| SARS-CoV-2 M inhibits IRF3 nuclear translocation, phosphorylation and ...
A, 1 34.5 protein inhibits phosphorylation of endogenous IRF3 in ...
N pro rapidly redistributes with IRF3 to mitochondria and cytoplasmic ...
IRF3 activation was inhibited in cells transiently expressing vhs upon ...
| IRF3 promotes the TRIF degradation. (a) HEK293 cells were ...
IRF3 sequestration is dependent on μNS's capacity to form viral ...
IRF3 undergoes liquid–liquid phase separation a–d, Images of GFP–IRF3 ...
Expression IRF3 in human microglia. Microglial cultures were treated ...
The levels of IRF3 are comparable in infected and uninfected primary ...
C10 inhibits IRF3 translocation to nucleus. PANC-1 cells were ...
Zebrafish foxo3b represses the transcriptional activity of irf3 and ...
IRF3 inhibits growth of HeLa cells. HeLa cells were cotransfected with ...
CLIC4 participates in LPS-induced IRF3 activation in macrophages. (A–C ...
figure supplement 2 Nuclear translocation of IRF3 after cGAMP ...
cGAMP binds to STING and activates IRF3 in a STING-dependent manner ...
aMPV/C P protein blocks IRF3 nuclear translocation. (A) HEK-293T cells ...
IRF3 nuclear translocation is inhibited in ISVP infected cells. A549 ...
miR-183 activates IRF3 phosphorylation. (A) Venn diagram visualizes ...
Nuclear translocation promotes TRIM26-mediated IRF3 degradation. (A ...
IRF3 regulates neuroinflammatory responses and the expression of genes ...
| TANK-binding kinase 1 (TBK1) isoforms associate with TBK1 and IRF3 to ...
Model of IRF3 nuclear receptor cross talk and biological consequence ...
A dominant negative IRF3 mutant inhibits IRF3-mediated attenuation of ...
(A) The effects of IRF7 variants on the IRF3 activity. 293T cells were ...
(PDF) SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical ...
ATRX interacts with IRF3 and modulates IRF3 activity. Stable ATRX ...
Region of IRF3 necessary for NSP1-induced degradation. (A) Summary of ...
TRIM11 reduces IRF3 activation and IFNb production. 293T cells were ...
Activation of IRF3 by posttranslational modifications. Human IRF3 and ...
Revisiting the role of IRF3 in inflammation and immunity by conditional ...
The capsid protein inhibits the dissociation of IRF3 from the MAVS-TBK1 ...
Illustration depicting function of IRF3 in production of INF1 and its ...
CSFV does not stimulate IRF3 translocation to the nucleus. (A to C) In ...
IRF3 compartmentalizes IRF7 in LLPS condensates a, Intracellular ...
Frontiers | IRF3 function and immunological gaps in sepsis
IRF3 inhibits inflammatory signaling pathways in macrophages to prevent ...
IRF3-dependent upregulation of MDA5. (a) Known IRF3 binding sites in ...
Subcellular localization of the variants of IRF3. Localizations of the ...
(A). MEF cells co-expressing Npro -cherry (red) and IRF3-GFP (green ...
Functional effect of RIG-I serine 8 substitutions on IRF-3 ...
TRAM interacts with IRF-3 and CBP and signals via IKKɛ and TBK1. (a ...
Map of final construct of recombinant plasmid DNA, pBud-H5-IRES-GFP ...
IRF3-nirs3 impairs the IFN- response in HCC cell lines. (a) Fusion ...
293T cells were transiently cotransfected with GFP-IRF3 plasmid ...
Avian Metapneumovirus Subgroup C Phosphoprotein Suppresses Type I ...
Mitogen-activated Protein Kinase-mediated Licensing of Interferon ...
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF ...
Structure of IRF-3 Bound to the PRDIII-I Regulatory Element of the ...
USP22 interacts with IRF3. (A) Immunoprecipitation (IP, with anti-GFP ...
CGAS/STING/IRF3 axis in type I IFN response of Irgm1−/− MEFs a ...
International Journal of Oncology
Frontiers | The Fish-Specific Protein Kinase (PKZ) Initiates Innate ...
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1 ...
SARS-CoV-2 Spike通过靶向IRF3 拮抗先天抗病毒免疫 - 知乎
Phosphorylation and location of interferon regulatory factor 3 (IRF3 ...
Hepatic gap junctions amplify alcohol liver injury by propagating cGAS ...
Interferon regulatory factor 3-CL, an isoform of IRF3, antagonizes ...
Inhibition of RIG-IN-induced nuclear translocation of GFP–IRF-3 by NS1 ...
Identification of a Novel in Vivo Virus-targeted Phosphorylation Site ...
Ni and CE(NiN) infections prevent nuclear translocation and ...
Frontiers | Interferon regulatory factor 3 mediates effective antiviral ...
The IRF-3 Transcription Factor Mediates Sendai Virus-Induced Apoptosis ...
Induction of IRF-3 nuclear localization by dsRNA. (A) Huh-7 or 293 ...
IKKε induces IRF-3 and IRF-7 activation. (A) Vero cells were ...
Domain mapping of binding region within IRF3. (A) Schematic ...
Loss of Interferon Regulatory Factor 3 in Cells Infected with Classical ...
The effect of P protein on degradation or phosphorylation of IRF3. (A ...
Interferon regulatory factor-3 is an in vivo target of DNA-PK | PNAS
Rubicon binds to IRF3. (A) Control and Rubicon-Flag-overexpressing ...
ASCC3 functions through an IRF-3-and IRF-7-dependent pathway. (A ...
Diverse mechanisms of cell death induced by GG25 and poly I:C. a ...
Glycogen synthase kinase 3 negatively regulates IFN regulatory factor 3 ...
Analysis of the inserted gene in pBud IRF3-H5-GFP by using restriction ...
Cytoplasmic RNA–DNA hybrids derived from R-loop processing activate ...
| CiKAT8 inhibits the combination of IRF3/IRF7 with ISRE response ...
Overexpression of IRF-3 reverts the LPS-mediated suppression of IFNA ...
Redistribution of a cytoplasmic protein, IRF-3, lacking an NLS ...
High Throughput Screening of FDA-Approved Drug Library Reveals the ...
Suppression of IRF-3 dominates over the IRF-7 stimulatory effect. (A ...
AgRP neuron cis-regulatory analysis across hunger states reveals that ...
aMPV/C P protein (101 to 200 aa) interacts with IRF3. (A) Schematic ...
Structural basis for concerted recruitment and activation of IRF-3 by ...
HEK293T cells were transfected with GFP-tagged IRF7 and FLAG-tagged ...
LPA maintains innate antiviral immunity in a pro-active state via ...
Site-specific acetylation of IRF3/IRF7 DBD abrogates LLPS a, Schematic ...
Involvement of IRF-3. (A) Immunofluorescence analysis. Vero B4 cells ...
Different DNA binding and interactions of IRF-3 and IRF-7 at two ...
水生所揭示抗病毒天然免疫的关键转录因子IRF3调控低氧信号转导通路的分子机制--中国科学院水生生物研究所
Zymosan:Adenovirus design and high uptake by macrophages. A Mutagenesis ...
Coimmunoprecipitation of NSs proteins with eGFP-IRF3. Selected ...
Frontiers | Grass Carp (Ctenopharyngodon idella) KAT8 Inhibits IFN 1 ...
Interferon regulatory factor 3 (IRF3) | Abcam
Ad-IRF3 activates pAkt in human microglia. (A) Microglial cultures were ...
