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Frontiers | Targeting MDMX for Cancer Therapy: Rationale, Strategies ...
MDMX inhibitors and their mechanism of action. SJ172550 is a compound ...
Schematic diagram representing MDMX interaction and transcriptional ...
Let’s get MDM2 and MDMX out of the shadow of p53 – Columbia University ...
Full article: MDMX in Cancer: A Partner of p53 and a p53-Independent ...
MDMX acidic domain regulates MDMX and p53 through intra-and ...
MDMX in Cancer: p53 and a p53-Independent Effector | BTT
Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 ...
A. Under normal conditions, MDM2 and MDMX function to maintain low ...
DNA damage inhibits MDMX suppression of p53 protein expression ...
Secondary interaction between MDMX and p53 core domain inhibits p53 DNA ...
MDMX acidic domain inhibits p53 DNA binding in vivo and regulates ...
Schematic representation of the MDMX protein, the mdmx mRNA and the ...
MDMX overexpression prevents p53 activation by Nutlin. a, U2OS ...
DNA Damage Induces MDMX Nuclear Translocation by p53-Dependent and ...
MDMX central domain inhibits N-terminal interaction with p53. (a ...
The effect of MDMX on MDM2-mediated p53 proteolysis depends on the ...
Immunohistochemistry patterns for MDM2, MDMX and P53. Three distinct ...
Knockdown of MDMX enhances p53 response to DNA damage. ( A ) U2OS cells ...
A Small-molecule MDMX inhibitor activates p53 leading to activation of ...
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia ...
Kinetics of p53 activation upon MDMX depletion in MEL202 cells. (A ...
PPT - DNA Damage-Induced Phosphorylation of MdmX at Serine 367 Enhances ...
MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond
MdmX Protein Is Essential for Mdm2 Protein-mediated p53 ...
Comparison of Mdm2 and Mdmx protein structure. The p53 binding domain ...
Structural basis of how stress-induced MDMX phosphorylation activates ...
Structural landmarks of MDM2 and MDMX proteins. Schematic... | Download ...
Mdm2 and MdmX Involvement in Human Cancer | SpringerLink
Mdm2 and MdmX partner to regulate p53 - Wang - 2012 - FEBS Letters ...
Proposed functional domains of the Mdm2 and MdmX oncoproteins. The ...
Schematic representation of the domains of Mdm2, Mdmx and p53 ...
MdmX slows cycling of p53-deficient cells. (a) Proliferation of ...
MDMX regulates p53 domain interaction and DNA binding. (A) p53-Cluc was ...
MDMX central domain inhibits interaction with p53. (a and b ...
MDMX enhances radiosensitivity in lung adenocarcinoma and squamous cell ...
The structure of MDMX protein. MDMX has four conserved domains ...
Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia ...
A Novel MDMX Transcript Expressed in a Variety of Transformed Cell ...
MdmX is required for p53 interaction with and full induction of the ...
Mdmx promotes genomic instability independent of p53 and Mdm2 - PMC
XI-011 inhibits MDMX gene transcription. (A) A reporter cell line ...
Autoinhibition of MDMX by intramolecular p53 mimicry | PNAS
Schematic of MDMX promoting TNBC metastasis and proposed targeting ...
AMP-Activated Protein Kinase Induces p53 by Phosphorylating MDMX and ...
MDMX is down-regulated during IR-induced p53 activation. In A ...
Expression of some MDMX target genes is FOXO-dependent. Analyses of ...
Expression of Mdmx-S protein is much lower compared to full-length Mdmx ...
Illustration of how MdmX is integrated into growth factor-mediated ...
MDMX (a) and dual MDM2 and MDMX (b) inhibitors for p53 activation ...
S367 phosphorylated MDMX preferentially localizes to the nucleus. (A ...
The MDMX Acidic Domain Uses Allovalency to Bind Both p53 and MDMX ...
The p53-MDM2/MDMX axis – A chemotype perspective - MedChemComm (RSC ...
Schematic representation of MDMX, p53 and RB. The different domains of ...
Schematic representation of the domain structures of p53, MDM2 and ...
MDM2 and MDMX: Alone and together in regulation of p53 - PMC
Small Molecule Inhibitors of MDM2-p53 and MDMX-p53 Interactions as New ...
Mdmx-Ser314 phosphorylation-mediated p53 modulation promotes macrophage ...
MDM2-MDMX binding is essential for MDMX-mediated suppression of p53 ...
Activation of p53 and destabilization of androgen receptor by ...
p53:MdmX and Mdm2:MdmX heterodimers act as reservoirs and generate ...
Analysis of p53-Independent Functions of the Mdm2-MdmX Complex Using ...
Regulation of MDMX. Different factors are involved in the regulation of ...
The roles and regulation of MDM2 and MDMX: it is not just about p53 ...
Inferring Leading Interactions in the p53/Mdm2/Mdmx Circuit through ...
DNA damage induces degradation of MDMX. ( A, B ) Cell lines with ...
Strategies for p53 Activation and Targeted Inhibitors of the p53-Mdm2 ...
International Journal of Oncology
Stabilization of the MDM2 Oncoprotein by Interaction with the ...
Comparison of sequences and structures of Mdm2/MdmX's p53-binding ...
Mechanistic Role of the Mdm2/MdmX Lid Domain in Regulating Their ...
The p53 inhibitors MDM2/MDMX complex is required for control of p53 ...
Mdmx/Hdmx regulates p53 acetylation. (a) Immunopre- cipitation of Mdm2 ...
Design of ultrahigh-affinity and dual-specificity peptide antagonists ...
The TP53 Website - MDM2 and MDM4 (MDMX)
(PDF) MDM4 (MDMX) localizes at the mitochondria and facilitates the p53 ...
