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NPC1 structure and proposed pathway of cholesterol binding (A ...
NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and ...
NPC1 controls TGFBR1 stability in a cholesterol transport-independent ...
Overexpression of NPC1 I1061T rescues the cholesterol accumulation ...
NPC1 Dloop mutant cannot rescue cholesterol export from lysosomes. (A ...
HPγCD alleviates cholesterol accumulation in NPC1 fibroblasts. Skin ...
Npc1 deficiency leads to cholesterol accumulation in enlarged late ...
NPC1 Disulfide bond-locked MLD and CTD fails to rescue cholesterol ...
(PDF) The cholesterol transporter NPC1 is essential for epigenetic ...
Cellular events involved in NPC1 disease: (a) cholesterol accumulation ...
NPC1 disease fibroblasts have altered cholesterol homeostasis and Ca² ...
Cholesterol Regulatory Phenotypes of NPC1 Null and ORP1L-Null Cells (A ...
Transport of LDL-derived cholesterol to the NPC1 compartment before the ...
Glycosylation inhibition reduces cholesterol accumulation in NPC1 ...
Amino acid substitution in NPC1 that abolishes cholesterol binding ...
Medium and cell cholesterol mass in NPC1 / and NPC1 / fibroblasts ...
Endolysosomal cholesterol export: More than just NPC1 - Lu - 2022 ...
Cholesterol and ganglioside immunohistochemistry (IHC) of Npc1 2/2 and ...
Intracellular cholesterol sequestration in Npc1 ؊ / ؊ neurons and ...
Rab7 interacts with the lysosomal cholesterol transporter NPC1 in an ...
Abnormal cholesterol accumulation in cerebellar Purkinje cells of Npc1 ...
(PDF) Fate of Endogenously Synthesized Cholesterol in Niemann-Pick Type ...
NPC1, intracellular cholesterol trafficking and atherosclerosis ...
Model for the hydrophobic handoff of cholesterol from NPC2 to NPC1, a ...
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle ...
Niemann-Pick C disease and mobilization of lysosomal cholesterol by ...
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by ...
Niemann-Pick Disease Type C (NPDC) by Mutation of NPC1 and NPC2 ...
Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for ...
A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport ...
Structures of NPC1, NPC2 and PTCH proteins. A, NPC1 bound to NPC2 (24 ...
Lysosomal cholesterol export reconstituted from fragments of Niemann ...
Cholesterol Handling in Lysosomes and Beyond: Trends in Cell Biology
(PDF) NPC 1 enables cholesterol mobilization during long‐term ...
Lysosomal cholesterol accumulation in differentiated Niemann–Pick ...
Frontiers | Mitochondrial Cholesterol in Alzheimer's Disease and ...
NPC1 −/− cells show increased levels of total cholesterol, accumulation ...
Figure 1 from Reduction of TMEM97 increases NPC1 protein levels and ...
Subcellular localization of Npc1 I1061T protein. A, NPC1 (red) and free ...
(PDF) Cholesterol Oxidation Products Are Sensitive and Specific Blood ...
(PDF) Inactivation of the Niemann Pick C1 cholesterol transporter 1 ...
JCI Insight - Species-specific differences in NPC1 protein trafficking ...
Figure 3 from NPC1, intracellular cholesterol trafficking and ...
NPC1 interacts with SLC38A9 and mediates mTORC1 inhibition upon ...
Transfer of Cholesterol by the NPC Team: Cell Metabolism
Simulations of NPC1(NTD):NPC2 Protein Complex Reveal Cholesterol ...
(PDF) Lysosomal cholesterol export reconstituted from fragments of ...
Expression of mutant NPC1 proteins in NPC1() cells. Cells were ...
Guilty until proven innocent: the case of NPC1 and cholesterol: Trends ...
(PDF) NPC1-mTORC1 signaling Couples Cholesterol Sensing to Organelle ...
Hypothetical model for cholesterol transfer between NPC2 and NPC1. (A ...
Cellular distribution of the NPC1 protein in relation to... | Download ...
The NPC1 protein encoded by the NPC1 gene regulates the transport of ...
Generation of an NPC1 mutant i³Neuron cell line. A The genomic ...
NPC1/NPC2 function as a tag team duo to mobilize cholesterol | PNAS
Clues to NPC1-mediated cholesterol export from lysosomes | PNAS
Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol ...
Clues to the mechanism of cholesterol transfer from the structure of ...
(PDF) Simulations of NPC1(NTD):NPC2 protein complex reveal cholesterol ...
Structure of N-terminal Domain of NPC1 Reveals Distinct Subdomains for ...
Genetic and Chemical Correction of Cholesterol Accumulation and ...
NPC1 cDNA transfection of CT-60 mutant NP-C CHO cells restores G M2 in ...
Cholesterol Trafficking: An Emerging Therapeutic Target for ...
Blocking the putative tunnel of NPC1 abolishes NPC1-mediated ...
Liver cholesterol accumulation and damage in Npc1-/- mice. (A-B ...
Human Placental Intracellular Cholesterol Transport: A Focus on ...
Reciprocal relationship between lysosomal cholesterol and... | Download ...
Secretion of lipids by Npc1 ؉ / ؉ and Npc1 ؊ / ؊ hepatocytes ...
Graphic illustration of the NPC1 protein. Secondary construction ...
Cholesterol accumulates at the limiting membrane of NPC1-deficient ...
Figure 3 from Reduction of TMEM97 increases NPC1 protein levels and ...
Models of NPC2–NPC1-mediated cholesterol transfer. The Ω loop (red ...
(PDF) NPC intracellular cholesterol transporter 1 (NPC1)-mediated ...
Inter-domain mobility is required for cholesterol transport by NPC1L1 ...
Selection of Cells with Cholesterol Trafficking Defects (A) Schematic ...
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol ...
Niemann-Pick NPC1: Sterols to the Rescue and Beyond: Chemistry & Biology
Unraveling the Connection: Cholesterol, Calcium Signaling, and ...
Superposition of NPC1, as modeled here (colored light grey) with ...
Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated ...
Lipids on Trial: The Search for the Offending Metabolite in Niemann ...
Identification of Surface Residues on Niemann-Pick C2 Essential for ...
Lysosome and endoplasmic reticulum quality control pathways in Niemann ...
Current Challenges in Understanding the Cellular and Molecular ...
(PDF) The role of NPC1L1 in cancer
Frontiers | The role of NPC1L1 in cancer
Enrichment of NPC1-deficient cells with the lipid LBPA stimulates ...
Structures of dimeric human NPC1L1 provide insight into mechanisms for ...
Selective Degradation Permits a Feedback Loop Controlling Annexin A6 ...
