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PylRS domain architectures and tRNA Pyl secondary structures in ...
PylRS innovation and its contribution to the future of research and ...
Crystal structures of the wild-type and PANCE-evolved PylRS variants ...
PylRS topology and α-amino group recognition in the active site. The ...
(A) Homology model of PylRS in complex with pyrrolysine (cyan) in the ...
Structural basis for the PylRS specificity to tRNA Pyl (a ...
Structure of PylRS. ( A ) A secondary structure diagram of PylRS with ...
| Domain organization and binding mode of PylRS. (A) PylRS is composed ...
Two routes of tRNA Pyl aminoacylation. (Upper) PylRS acylates tRNA Pyl ...
| (A) Combining PylRS opt mutations with N166S improves incorporation ...
Phylogenetic distribution of Pyl decoding. (A) To date, the pylRS genes ...
Comparison of PylRS structures.a, DhPylRS–tRNAPyl complex (PDB code ...
Activity mapping of candidate PylRS enzymes and Pyl tRNAs, and ...
Structure and evolution of PylRS and the Pyl operon. (A) Key hydrogen ...
Directed evolution of PylRS variants with specificity for hydroxy acids ...
Update of the Pyrrolysyl-tRNA Synthetase/tRNAPyl Pair and Derivatives ...
Frontiers | Linker and N-Terminal Domain Engineering of Pyrrolysyl-tRNA ...
Crystal structures reveal an elusive functional domain of pyrrolysyl ...
Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal ...
华大研究院揭示新型PylRS/tRNAPyl相互正交的分子机制 - 生物通
The essential four components of the Pyl incorporation machinery ...
Pyrrolysyl-tRNA Synthetase with a Unique Architecture Enhances the ...
Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically ...
Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic ...
Expanding the Scope of Orthogonal Translation with Pyrrolysyl-tRNA ...
Polyspecific pyrrolysyl-tRNA synthetases from directed evolution | PNAS
Both HMET1 PylRS/tRNA Pyl pairs are active and orthogonal in H ...
Engineered PylRS–tRNAPyl system to read-through endogenous PTCs for ...
Evolving the N‐Terminal Domain of Pyrrolysyl‐tRNA Synthetase for ...
Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of ...
(PDF) Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the ...
Addgene: Ma-PylRS-lib1 Pooled Library
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic ...
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine | PNAS
Rapid Identification of Functional Pyrrolysyl-tRNA Synthetases via ...
(A) Pyrrolysine is synthesized from 2 equivalents of lysine in 3 steps ...
Mx1201 PylRS/PylT pair is active and orthogonal in mammalian cells ...
Encoding two distinct ncAAs using mutually orthogonal HMET1 PylRS/tRNA ...
Structure of the PylRS•tRNA Pyl complex from D. hafniense (PDB ID 2ZNI ...
Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs - PMC
tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA ...
The A73 discriminator of tRNA Pyl 2 and a shorter motif 2 loop in ...
The de novo engineering of pyrrolysyl-tRNA synthetase for genetic ...
Structures of pyrrolysine derivatives. (A and B) Diastereomers of the ...
PylSn and the Homologous N-terminal Domain of Pyrrolysyl-tRNA ...
Pyrrolysine Aminoacyl-tRNA Synthetase as a Tool for Expanding the ...
Identifying ΔNPylRS/PyltRNA pairs that are active and orthogonal in E ...
Aminoacylation of tRNA 2′- or 3′-hydroxyl by phosphoseryl- and ...
*An alternative direct pathway wherein pyrrolysine is charged to tRNA ...
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase ...
Pyl biosynthetic pathway evolution via Alt-PANCE A Pyl biosynthesis ...
Crystal structures of AMP and BocLysAMP bound to PylRS. (a, b) The F o ...
(A) The active site of Pyl. (B) The contoured deep substrate binding ...
Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular ...
Distinct genetic code expansion strategies for selenocysteine and ...
Crystallographic analysis of PylRS-AA. (A) Amino acid binding pocket of ...
pyrrolysyl-tRNA synthetase activity | Semantic Scholar
| Promiscuous activity of wild-type MaPylRS. a, The ⍺-amines of ...
Continuous evolution and characterization of chimeric pyrrolysyl-tRNA ...
Structural Basis for Genetic-Code Expansion with Bulky Lysine ...
Pyrrolysyl‐tRNA synthetase variants reveal ancestral aminoacylation ...
Evaluation of the in vivo safety of the PylRS–tRNAPyl system a,b, Body ...
| Structure of MmPylRS NTD complex with tRNA Pyl . R61 and H63 located ...
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