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SHARPIN and HOIP form a novel LUBAC complex with the ability to induce ...
Mechanisms Underlying Trimeric LUBAC Stabilization HOIL-1L and SHARPIN ...
SHARPIN is a novel component of the LUBAC complex. a, Schematic ...
(PDF) Reduced SHARPIN and LUBAC formation may contribute to CCl4 - Or ...
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB ...
Reduced SHARPIN and LUBAC Formation May Contribute to CCl₄- or ...
Reduced SHARPIN and LUBAC Formation May Contribute to CCl4- or ...
LUBAC Recruitment to the CBM Complex in ABC DLBCL Depends on cIAP1/2 ...
Schematic representation of the LUBAC components, SHARPIN, HOIP and ...
Schematic representation of the members of the LUBAC complex, RBCK1 ...
AlphaFold-predicted core domain structures of LUBAC subunits (A) The ...
Structure of the catalytic core of HOIP. a, Composition of LUBAC ...
Platelet SHARPIN regulates platelet adhesion and inflammatory responses ...
Functional domains of the three linear ubiquitin chain assembly complex ...
The UBL Domain of SHARPIN Specifically Binds to the UBA Domain of HOIP ...
| A schematic diagram showing the domain architectures of SHARPIN ...
SHARPIN affects the stability of LUBAC. a, Reduction of HOIP and ...
A proposed mechanistic model on how SHARPIN regulates TNF-induced NF-κB ...
Synergistic involvement of the NZF domains of the LUBAC accessory ...
LUBAC-DUB complexes. LUBAC exists in distinct complexes with the DUBs ...
SHARPIN at the nexus of integrin, immune, and inflammatory signaling in ...
Schematic representation of the domain organisation of LUBAC subunits ...
Western blot analysis of RNF31, RBCK1 and SHARPIN for breast tumors. A ...
Serine 165 phosphorylation of SHARPIN regulates the activation of NF-κB ...
HOIL-1L E3 activity negatively regulates LUBAC functions in vitro a ...
The UBL domain of SHARPIN mediates binding to integrin. (A) Schematic ...
LUBAC expression and linear ubiquitylation are increased in LSCC ...
Targeting the Linear Ubiquitin Assembly Complex to Modulate the Host ...
Lack of interaction between NEMO and SHARPIN impairs linear ...
Adequate host response against IAV infection requires SHARPIN and TLR3 ...
Expression of genes constituting the linear ubiquitin assembly complex ...
How does LUBAC use cFLIP linear ubiquitination to promote TNFα-induced ...
SHARPIN as an important mediator for regulating the physiological ...
Structural simulations of AD-associated SHARPIN SNP sites. SHARPIN ...
The composition of LUBAC and the activity of the RBRs. (A) Domain ...
SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD ...
Biallelic human SHARPIN loss of function induces autoinflammation and ...
SHARPIN Antibody - BSA Free (NBP2-04116): Novus Biologicals
HOIP UBA Domain Adopts Different Conformations to Interact with SHARPIN ...
Comparison of linear ubiquitin chain synthesis by different LUBAC ...
| Difference between SHARPIN presence and absence in regulating the ...
The linear ubiquitin chain assembly complex (LUBAC) generates ...
Molecular dynamics simulation modeling of the effect of the SHARPIN ...
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in ...
Designing SHARPIN mutants using a SHARPIN UBL domain model. (A ...
HOIL-1L ubiquitinates all LUBAC subunits followed by HOIP-mediated ...
Sharpin deficiency in Treg causes cpdm-like skin inflammation. a ...
ASC is linear ubiquitinated by LUBAC in 293T cells and in vitro. (a ...
The paracaspase MALT1 dampens NF‐κB signalling by cleaving the LUBAC ...
Loss of HOIL-1L E3 activity increases LUBAC activity in vitro a, b ...
Diagram showing the involvement of LUBAC in LMP1 signaling ...
HOIL-1L ubiquitinates all LUBAC subunits, HOIP conjugates linear ...
Cooperative Domain Formation by Homologous Motifs in HOIL-1L and ...
Frontiers | Non-lysine ubiquitylation: Doing things differently
An illustration of the primary upstream and downstream signaling ...
(PDF) New Look of EBV LMP1 Signaling Landscape
Composition of LUBAC. Schematic of the domain composition of HOIP ...
Frontiers | Advances in the Structural and Physiological Functions of ...
Chinese Academy of Sciences Shanghai Branch
February 2016 Activation of NF-κB pathway and suppression of cell death ...
LUBAC: Current Biology
Biochemistry, Pathophysiology, and Regulation of Linear Ubiquitination ...
TNFR1 canonical pathway. (A) Upon TNFR1 activation linear ubiquitin ...
Ikeda Laboratory – Graduate School of Frontier Biosciences, Osaka ...
Targeting the HOIL-1L/SHARPIN Interaction Using an α-Helical-Stapled ...
Startseite
Linear Ubiquitination of NEMO Negatively Regulates the Interferon ...
Structural Insights into SHARPIN-Mediated Activation of HOIP for the ...
Cyclophilin J limits linear ubiquitin signaling and controls colorectal ...
| The linear ubiquitination machinery. Linear ubiquitin chains are ...
SLST Researchers Report a Novel Mechanism of Linear Ubiquitination ...
Oncology Letters
Fine mapping of the integrin binding site in SHARPIN. (A) Interaction ...
Advancements in Immunology: SHARPIN’s Impact - The Aartery Chronicles (TAC)
HOIPINs suppress the RING-HECT-hybrid reaction of LUBAC. a HOIPIN-8 ...
LUBAC-mediated linear ubiquitination: a crucial regulator of immune ...
Induced NF-κB activity in cells with mutant OTULIN. (A) OTULIN mutants ...
HOIP deficiency. (A) Relative HOIP mRNA levels in SV40-immortalized ...
AD-associated SNP sites and the amino acid alignment of SHARPINs from ...
In vitro assessment and predicted crystal structure model of RNF31 ...
Fig. 3, [Schematic representation of LUBAC, which...]. - Innovative ...
Integrin beta 1 inhibition alleviates the chronic hyperproliferative ...
Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 ...
