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Targeting TPC2 activity affects histamine-evoked P-selectin cell ...
Construction of the stable human TPC2 (hTPC2)-expressing cell line ...
Lsm12 mediates the apparent association of NAADP to TPC2 and cell ...
Correlation of endogenous TPC1 and TPC2 expression with cell cycle ...
TPC2 overexpression markedly induced programmed cell death during ...
TPC2 depletion increases metastatic melanoma cell invasion. (A ...
Crosstalk between TPC2 and IP3R regulates Ca2+ signals: Trends in Cell ...
TPC1 and TPC2 do not affect TRPML1 function. A and B , whole- cell ...
Structural basis for inhibition of the lysosomal two-pore channel TPC2 ...
TPC2 promotes choroidal angiogenesis and inflammation in a mouse model ...
溶酶体 TPC2 和 TRPML1 生成的自主 Ca2+ 纳米域的光学分析,Cell Calcium - X-MOL
Diagrammatic depiction of TPC2 role in metabolic reprogramming in ...
Hypoxia-induced TPC2 transcription and glycosylation aggravates ...
TPC2 targeting evolution: Leveraging therapeutic opportunities for ...
Frontiers | Endolysosomal Ca2+ Signaling in Cancer: The Role of TPC2 ...
TPC2 localizes to PDGs in MEG-01 cells. (A–E) Spinning-disk confocal ...
TPC2 controls pigmentation by regulating melanosome pH and size | PNAS
MITF signalling pathways and proposed effects in TPC2 knockout melanoma ...
TPC2 and TRPML1 channels generate independent Ca 2þ nanodomains. Ca 2 ...
Targeting TPC2 sensitizes acute lymphoblastic leukemia cells to ...
TPC1 and TPC2 are not expressed in the plasma membrane in MEG01 and ...
Two-pore channels control Ebola virus host cell entry and are drug ...
Silencing TPC2 expression attenuates the rate and extent of Ca 2+ in fl ...
TPC2 is the pore-forming subunit of an NAADP-gated channel. A ...
TPC2 co-immunoprecipitates with STIM1 and Orai1 in MEG01 cells. Cells ...
TPC2 expression in the melanoma patient dataset and the generation of a ...
Role of lysosomal channel protein TPC2 in osteoclast differentiation ...
tPC2 signaling inhibited autophagy by increasing lysosomal ph in heLa ...
The endosomal calcium channels TPC1 and TPC2 are necessary for EBOV ...
Levels of TPC1 and TPC2 mRNA relative to β-actin mRNA (A). Western-blot ...
TPCs are N-glycosylated. A, schematic depictions of TPC1 and TPC2 ...
TPC2 regulates melanosomal pH to modulate pigmentation. (a) Histogram ...
Diagrammatic depiction of TPC2 role in metastatic melanoma. The ...
TPC2 localizes to melanosomes in pigment cells. (a) GFP-tagged TPC2 ...
A gain-of-function TPC2 variant R210C increases affinity to PI(3,5)P2 ...
TPC2 overexpression alkalizes the lumen of PDGs. (A) Localization of ...
Ions switch off darkness: role of TPC2 in melanosomes - Patwardhan ...
Co-activation of endogenous TPC2 evokes global Ca²⁺ signals a, b Effect ...
TPC2 targeted to the plasma membrane is uncoupled from ryanodine ...
TPC2 mediates new mechanisms of platelet dense granule membrane ...
Effect of TPC2 overexpression on autophagy. A , overlaid confocal ...
TPC2 knockdown inhibited neuronal differentiation from mouse ES cells ...
TPC2 localizes to PDGs in primary MKs. (A) Spinning-disk confocal ...
TPC2 agonists synergistically activate TPC2 a Differential effects of ...
Neurodegenerative Lysosomal Storage Disorders: TPC2 Comes to the Rescue!
Lysosomal TPC2 channels disrupt Ca2+ entry and dopaminergic function in ...
Agonist-mediated switching of ion selectivity in TPC2 differentially ...
Cell fate bias in tpc2⁻ cells. (a) Chimeric development. Exponentially ...
TPC2 agonists differentially affect lysosomal pH and proton ...
TPC2 signaling inhibited the progression of autophagy during neural ...
Inside-out recordings of plasma membrane-targeted TPC2 show altered ...
The growth and developmental phenotypes of tpc2 − cells are dependent ...
TPC2 signaling increased lysosomal pH to suppress autophagy ...
Early developmental responses are altered in tpc2 − cells. a Schematic ...
The two pore channel TPC2 is dispensable in pancreatic β-cells for ...
| Schematic representation of the role of TPC2 in the... | Download ...
TPC2 did not inhibit general endosomal-lysosomal degradation in HeLa ...
Frontiers | Endolysosomal transient receptor potential mucolipins and ...
Targeting the two-pore channel 2 in cancer progression and metastasis
Ca 2 , not mTOR, was involved in TPC2-induced autophagosome ...
Frontiers | Two-pore channel regulators - Who is in control?
A Role for Two-Pore Channel Type 2 (TPC2)-Mediated Regulation of ...
P-selectin-dependent leukocyte adhesion is governed by endolysosomal ...
Gene editing and synthetically accessible inhibitors reveal role for ...
TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion ...
The Two-pore channel (TPC) interactome unmasks isoform-specific roles ...
Altered properties of acidic vesicles in tpc2⁻ cells. a Intracellular ...
Small molecule agonist TPC2-A1-N increases intracellular Ca2 ...
EBOV enters cells through LE/Lys that contain both NPC1 and TPC2. (a ...
Two Pore Channel 2 (TPC2) Inhibits Autophagosomal-Lysosomal Fusion by ...
Proliferation, migration, and invasion in WT and TPC2−/− MNT-1 cells ...
Developmental delay of tpc2⁻ cells. Parental Ax2 and tpc2⁻ cells were ...
Ca²⁺ responses in tpc2⁻cells. a Ax2- and tpc2-null cells were developed ...
Tissue and subcellular expression of mammalian TPC2.a, Hydropathy plot ...
Targeting Two-Pore Channels: Current Progress and Future Challenges ...
Lack of effect of overexpressed TPC isoforms on PAL profiles. A ...
Pathological tau disrupts lysosomal Ca 2+ and pH homeostasis by ...
Bringing lysosomal patch clamp recording to HTS | AXXAM
Two-Pore Channels in Cancer Hallmarks: An Update Review – Biomedical ...
Rabbit TPC1, TPC2, and TPC3 are distantly related and exhibit ...
