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In Situ Architecture and Cellular Interactions of PolyQ Inclusions: Cell
Proposed mechanisms of cytotoxicity of the expanded polyQ protein and ...
Molecular and structural architecture of polyQ aggregates in yeast | PNAS
Cartoon of proposed polyQ function in protein interaction. Left: a ...
PolyQ protein aggregates disturb different cellular processes. (A ...
Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal ...
The structural properties of polyQ helices are tract length dependent ...
PolyQ aggregates colocalized and coprecipitated with Hsc70 and Relish ...
Co-evolution of polyQ repeats in sets of physically interacting ...
Autophagy preferentially degrades non-fibrillar polyQ aggregates ...
Aging-induced polyQ aggregates can be differentiated from osmotically ...
A Schematic representation of the constructs used to express polyQ ...
PolyQ toxicity depends on amino acids flanking the polyQ region. Yeast ...
Effects of EGb 761 on degradation of polyQ proteins and polyQ ...
Transcriptional deregulation in therapeutic strategies of polyQ ...
Evolutionary history of polyQ repeats in primates and their ...
The polyQ stretch contributes an -helical structure to thio-polyQ ...
Between Interactions and Aggregates: The PolyQ Balance - PMC
PolyQ aggregates exhibit slow nucleation dynamics and a power-law ...
Expanded polyQ triggers ER stress through proteasomal dysfunction. ( A ...
PolyQ aggregates undergo frequent fusion and fragmentation events in ...
PolyQ peptide designs based on the template Trpzip2 (SWTWENGKWTWK-NH2 ...
Co-evolution of polyQ repeats in pairs of functionally related ...
PolyQ expansion in Ataxin-1 and Htt N548 proteins increases ...
The 3D structure of the polyQ tract and flanking residues ...
The polyQ domain of Whi3 has a self-templating activity (A) Sequence of ...
PolyQ expansion promotes TBP to preferentially form aggregates in the ...
Analyses of polyQ aggregates. (A) Confocal images (top panel) showing ...
Guduchi and Madhuyashti feeding exaggerate polyQ mediated... | Download ...
PolyQ ATXN3 proteins accumulate in the CSF and plasma from individuals ...
The polyQ tract of TBP forms a helix stabilized by Gln side chain to ...
Structures adopted by polyQ peptides as a function of tract length: a ...
PolyQ proteins are over-represented in specific functional clusters of ...
Mdm20 stimulates polyQ aggregate formation in HEK293 cells. A. The ...
Model for how polyQ expansion may alleviate polyQ toxicity. Soluble ...
Secondary structure of polyQ fragments of different lengths. A. Q18. B ...
(PDF) Expanded polyQ aggregates interact with Sarco-endoplasmic ...
Full article: Visualization of autophagic structures near solid polyQ ...
(A) Exemplified filter retardation analysis to visualize polyQ ...
Molecular and structural architecture of polyQ aggregates in yeast ...
The soluble -sheet monomer of the expanded polyQ protein is ...
Dynamics of PolyQ Peptides (A, B) The fraction of secondary structure ...
Scaling of the polyQ domain as a function of polyQ length and ...
Hypothetical model for the pathway of polyQ aggregation and its ...
PolyQ length-based molecular encoding of vocalization frequency in ...
The Protein Structure Context of PolyQ Regions
| Representation of pathogenic polyQ proteins and known modulating ...
The effects in the eye of ataxin-2 bearing different polyQ repeat ...
SGTA colocalized with polyQ aggregates in HD model cells. a ...
(PDF) PolyQ Database-an integrated database on polyglutamine diseases
Interactomes of functionally related polyQ proteins (A) Schematic ...
Proposed model of early events in polyQ pathogenesis. Existing evidence ...
PolyQ-induced growth arrest correlates with polyQ tract length and ...
Domains overrepresented in proteins that interact with human polyQ ...
(PDF) The Protein Structure Context of PolyQ Regions
Summary of therapeutic strategies in polyQ diseases. Molecules ...
PolyQ length affects GST-FLAG-HTTexon1 quantification by MSD assay ...
Mutant polyQ proteins interact with TERA/VCP/p97 in the human brain.(a ...
Increased number of polyQ repeats correlates with formation of Htt ...
Summarizes the suitability of other polyQ diseases for the evaluation ...
The structures of polyQ helices feature sc(i) → mc(i −4) hydrogen ...
PolyQ Disease: Too Many Qs, Too Much Function?: Neuron
The Polymorphic PolyQ Tail Protein of the Mediator Complex, Med15 ...
Designer polyQ fusion proteins sequester USP7/HDM2 for modulating P53 ...
A comparison of protein annotation in PolyQ and | Download Table
Aggregation of polyQ‐extended proteins is promoted by interaction with ...
中大研發神經退化性疾病抑制劑為治療polyQ疾病帶來曙光 | 香港中文大學傳訊及公共關係處
PolyQ-expanded AR forms 2% SDS-resistant aggregates and inclusion ...
(PDF) Sodium and Chlorine Ions Length-Dependent Structural ...
Polyglutamine (PolyQ) Diseases: Navigating the Landscape of ...
Formation of toxic oligomers of polyQ-expanded Huntingtin by prion ...
HSPB7 reduces polyQ-induced toxicity in cells and in vivo ...
Pathogenic polyQ-htt causes inefficient mitochondrial cargo degradation ...
8R10Q reduced the compactness of polyQ-rich peptide (K 2 Q 20 K 2 ...
Copper-inducible model. (A) Representation of the polyQ-GFP expression ...
Identification of polyQ-associated proteins by immunoprecipitation and ...
Ataxin-3, S5a, Eps15, and Hrs UIMs are recruited to polyQ-expanded Htt ...
Establishment of a polyQ-expanded ATXN2 TR-FRET-based immunoassay. a ...
Structure and oligo-/poly-merization of polyQ, polyA, polyQA and mixed ...
Polymerization of polyQ/QY proteins in [PIN+] cells. A, schematic ...
PolyQ-length-dependent interaction between HAP1 and AR. ( A ) Diagrams ...
PolyQ: a database describing the sequence and domain context of ...
Effect of E64d and pepstatin A on the level of polyQ72 and ...
(a) Number of proteins that interact with both polyQ-binding proteins ...
Two models for polyQ-mediated toxicity and its suppression by the ...
UBL3 Interacts with PolyQ-Expanded Huntingtin Fragments and Modifies ...
Essential Role of Coiled Coils for Aggregation and Activity of Q/N-Rich ...
PolyQ-expressing cells are more susceptible to stress-induced ...
TR-FRET analysis in human cell culture materials. a Determination of ...
HTT-polyQ inclusion formation requires centriolar satellites and the ...
(A) Length of the imperfect polyQs. (B) Length of the longest pure ...
Extracellular Q-peptides "seed" aggregation of cytoplasmic Htt-polyQ ...
PolyQ-Expansion Causes Mitochondria Fragmentation Independent of ...
Fig. 3. | Microbiology Society
Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo ...
Expanded poly(Q)-containing proteins are protected from degradation ...
Mind your Qs: polyQ-binding protein 5 scaffolds the nucleolus
PolyQ-Expanded Mutant Huntingtin Forms Inclusion Body Following ...
Frontiers | Intranuclear inclusions of polyQ-expanded ATXN1 sequester ...
Sequence Context Influences the Structure and Aggregation Behavior of a ...
Graphical illustration of the [IMAGE] | EurekAlert! Science News Releases
