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Schematic representation of the key enzymatic function of IDH1 and IDH1 ...
Implications of Concurrent IDH1 and IDH2 Mutations on Survival in ...
IDH1 is a cytosolic protein with enzymatic activity. A point mutation ...
Representation of wild type IDH1 homodimers shifting between the ...
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted ...
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular ...
The role of IDHs. IDH1 is located in the cytosol and the peroxisomes ...
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a ...
IDH1 mutations in five head and neck cancer studies (cBioPortal). A ...
The Landscape of the Anti-Kinase Activity of the IDH1 Inhibitors
| The overexpression of IDH1 promoted cell proliferation of ...
IDH1 and IDH2 mutations in pediatric acute leukemia. - Abstract ...
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis
IDH1 deficiency attenuates gluconeogenesis in mouse liver by impairing ...
Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid ...
IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and ...
Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic ...
Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through ...
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism. - Abstract ...
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity ...
IDH1 and IDH2 Mutations in Tumorigenesis: Mechanistic Insights and ...
LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to ...
IDH1 and IDH2 Mutations in Gliomas | NEJM
IDH1 mutation in different glioma groups based on DNA sequencing. A ...
MetaMapp- visualizing metabolomics networks: Effect of IDH1 mutations ...
IDH1 demonstrates sialidase activity A Crystal structure of isocitrate ...
Mutant IDH1 Promotes Glioma Formation In Vivo: Cell Reports
| IDH1 promoted cell migration and invasion and IDH1 knockout decreased ...
IDH1 knockout led to a decrease in colony formation ability and ...
Clinical development of IDH1 inhibitors for cancer therapy - Cancer ...
Wild-type IDH1 maintains NSCLC stemness and chemoresistance through ...
IDH1 and IDH2: Not Your Typical Oncogenes: Cancer Cell
IDH1 Polyclonal Antibody, Invitrogen 100 μL; Unconjugated:Antibodies ...
Sequencing chromatogram of IDH1 in two different patients. (A) Patient ...
The acetylation of MDH1 and IDH1 is associated with energy metabolism ...
IDH1 in AML & TIBSOVO® (ivosidenib tablets) Mechanism of Action
Frontiers | Differential metabolic alterations in IDH1 mutant vs ...
IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase ...
IDH1 regulates human erythropoiesis by eliciting chromatin state ...
Expression level distribution of IDH1 in RCC and cell lines. (A ...
Frontiers | Recent advances of IDH1 mutant inhibitor in cancer therapy
IDH1 mutation inhibits differentiation of astrocytes and glioma cells ...
Mutant IDH1 Differently Affects Redox State and Metabolism in Glial ...
IDH1 treatment increases multimer binding and cytokine production in ...
IDH1 and IDH2 mutations as novel therapeutic targets: current ...
Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable ...
IDH1 promote the proliferation of colon adenocarcinoma cells. A The ...
IDH1 Mutations Disrupt Blood, Brain, and Barriers: Cancer Cell
Site of mutation in IDH1 gene is R-132 and in IDH2 gene is R-172 ...
IDH1 and IDH2 mutations causes build up of 2-hydroxygluatrate (2-HG ...
Schematic representation of IDH1 and IDH2 mutations determining the ...
Overexpression IDH1 suppressed RCC cell growth in vivo. (A ...
IDH1 Mutation Induces HIF-1α and Confers Angiogenic Properties in ...
Overview of IDH1's biological role in normal cellular functions and the ...
Metabolic adaptations in cancers expressing isocitrate dehydrogenase ...
Frontiers | IDH1: Linking Metabolism and Epigenetics
Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML ...
PPT - Structure of IDH1-R132H PDB: 3MAR, adapted from Yang B et al ...
Cartoon of isocitrate dehydrogenase 1 (IDH1) wild-type cells (blue) and ...
mRNA expression levels of enzymes involved in glucose metabolism in ...
肿瘤医生应该知道的生物标志物之：IDH1/IDH2 - 知乎
Glutamine Metabolism in Cancer Stem Cells: A Complex Liaison in the ...
Targeting Cancer Metabolism
Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations ...
Figures
Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular ...
An acidic residue buried in the dimer interface of isocitrate ...
Isocitrate dehydrogenase/IDH1 Protein Overview | Sino Biological
IDH1-dependent α-KG regulates brown fat differentiation and function by ...
Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 ...
Human Isocitrate Dehydrogenase 1/IDH1 Antibody MAB7049: R&D Systems
Frontiers | Biological Roles and Therapeutic Applications of IDH2 ...
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on ...
Figure 2 from Role of isocitrate dehydrogenase 1/2 (IDH 1/2) gene ...
Biochemical, Cellular, and Biophysical Characterization of a Potent ...
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic ...
Schema of Altered Metabolic Pathways in IDH 1/2 Mutations. Wild type ...
The expression of the isocitrate dehydrogenase 1 (IDH1) in ...
Hyperthermia as a Potential Cornerstone of Effective Multimodality ...
Isocitrate Dehydrogenase Mutations in Glioma: Genetics, Biochemistry ...
Profiling the Effect of Targeting Wild Isocitrate Dehydrogenase 1 (IDH1 ...
The Leukemic IDH1/2 Mutations Impair Myeloid and Erythroid Cell ...
(PDF) Isocitrate dehydrogenase mutations in gliomas
Consequences of IDH1/2 Mutations in Gliomas and an Assessment of ...
The regulatory mechanisms and inhibitors of isocitrate dehydrogenase 1 ...
Normal and deregulated isocitrate dehydrogenase (IDH) signaling in ...
Mutant IDH regulates glycogen metabolism from early cartilage ...
Catalytic functions of the wild-type and mutated IDH1/IDH2 enzymes. In ...
Mutant IDH inhibitors induce lineage differentiation in IDH-mutant ...
Molecular Medicine Reports
Effect of IDH1/2 mutations on metabolism. [Color figure can be viewed ...
Proteomic Analysis Uncovers Enhanced Inflammatory Phenotype and ...
Capturing the Dynamic Conformational Changes of Human Isocitrate ...
Molecules | Free Full-Text | Consequences of IDH1/2 Mutations in ...
经典重读丨Nature肿瘤中IDH1突变和2-HG - 知乎
Functional implications of IDH1-mutation-induced alterations in the ...
Clinical trial of drugs or small molecules on gliomas containing the ...
