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POLQ Has a Unique Domain Architecture Enabling Its Diverse Functions ...
POLQ seals post-replicative ssDNA gaps to maintain genome stability in ...
Clinical Challenges Associated with POLQ Inhibitors. To ensure clinical ...
Complementation of the polymerase activity of POLQ rescues DNA damage ...
TINS are increased in tumors with high POLQ expression and with BRCA ...
Sensitivity of POLQ DNA polymerase to inhibitors. ( A ) ddNTP ...
(PDF) POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in ...
POLQ is significant for PDAC progression and overall survival. (A ...
-Structure of the Polq gene and transcripts. (A) An open reading frame ...
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human ...
POLQ suppresses chromosomal translocation in vivo. (A) Representative ...
POLQ domain structure, conservation and exon arrangement. ( A ) In the ...
Polq is required for survival following Cas9-induced DNA DSBs All ...
Flow chart of molecular mechanism underlying the effect of POLQ on ...
Expression of POLQ in SACC. (A) qRT‐PCR for POLQ mRNA in SACC‐83 and ...
Polq gene targeting strategy. (A) Schematic representation of a part of ...
polQ is required for proper RPA3⁺ foci dynamics, acentric DNA ...
Unique template dependent DNA polymerase activity of POLQ ...
Experimental Strategy and Gene Targeting of POLQ Locus (A) Schematic ...
POLQ Screening Platform - 资料下载 - 爱思益普生物-蛋白平台
Induction of the DNA-Repair Gene POLQ only in BRCA1-mutant Breast ...
Polq confers resistance to DNA-protein crosslinking agents (A) Bar ...
POLQ performs MH-mediated templated insertions. (A) A model of ...
Conservation of POLQ central domain length and polymerase domain ...
POLQ Gene - GeneCards | DPOLQ Protein | DPOLQ Antibody
Expression patterns of POLQ in HCC tissues and normal tissues revealed ...
Disruption of Pol polymerase core motif. (A) Scheme of the mouse Polq ...
Protein POLQ - Overview | canSAR.ai | canSAR.ai
DNA polymerase POLQ and cellular defense against DNA damage. - Abstract ...
Loss of Polq contributes to chromosomal instability both spontaneously ...
Relationship between POLQ expression and tumor characteristics in ...
Exploration of regulatory mechanism of POLQ on HCC. A, B A human ...
Association of POLQ overexpression with the somatic mutation load and ...
Vertebrate POLQ and POLβ Cooperate in Base Excision Repair of Oxidative ...
Colony-forming ability of Polq +/+ and −/− clonal cell lines after 1 h ...
Effect of POLQ siRNA on normal cells. A, POC cells treated with POLQ ...
Detection of POLQ expression. Left: northern blot analysis of human ...
POLQ Overexpression Is Associated with an Increased Somatic Mutation ...
Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy: Trends ...
Structure of Polq-HLD and ATPase Core (A) Overview of the Polq-HLD ...
BIOCELL | Free Full-Text | DNA polymerase θ (POLQ): A druggable DNA ...
Possible Modes of DNA Binding to the Polq-HLD Tetramer, and their ...
Structure of the Polq-HLD Tetramer Overview of the interfaces between ...
DNA Polymerase θ: A Unique Multifunctional End-Joining Machine
DNA polymerase θ (POLQ) is important for repair of DNA double-strand ...
DNA polymerase θ (POLQ), double-strand break repair, and cancer - PMC
Human DNA Polymerase Theta assay
(PDF) Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy
Expression and Structural Analyses of Human DNA Polymerase θ (POLQ ...
POLQ/Polθ expression is regulated by RAR signaling. a, b PEO1 and ...
Pol θ mediated end joining | Ramsden lab
Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes ...
Anti-DNA polymerase theta Antibody Products | Biocompare
(PDF) Genetic determinants of cellular addiction to DNA polymerase theta
Multifaceted Nature of DNA Polymerase θ
Human DNA Polymerase Theta (POLQ) [IMAGE] | EurekAlert! Science News ...
POLQ能否成为继PARP后下一个合成致死的明星靶点? - 脉脉
Modeling of the Interaction Between Polq-HLD and DNA (A) Overview of ...
Contribution of Microhomology to Genome Instability: Connection between ...
Characterization of DNA-Binding and ATPase Activity of Polq-HLD (A ...
Research Projects | Endocrine Neoplasia Research Group | Washington ...
RTEL-1 and POLQ-1 promote telomere-ITS DNA synthesis and end-to-end ...
Mammalian Polymerase Theta Promotes Alternative-NHEJ and Suppresses ...
DNA Polymerase θ (POLQ), His-Tag, SUMO-Tag Recombinant DNA PolO 101945
Tertiary structure of the helicase, POLQ-like protein. | Download ...
Structure and Comparison of Polq-HLD Domains 3 to 5 (A) Close-up view ...
The DNA Damage Response | BellBrook Labs
IF:19.328|POLQ“封条”连接ssDNA缺口维持BRCA缺陷癌细胞基因组的稳定 - 知乎
Polq/53bp1 double knockout cells accumulate non-productive HR ...
POLQ-mediated repair is characterized by single nucleotide homology. A ...
Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic ...
"Polymerase Theta (PolQ) is Essential to Repair a Subset of DNA Breaks ...
Polymerase θ Coordinates Multiple Intrinsic Enzymatic Activities during ...
Recombinant Human DNA polymerase theta(POLQ),partial (CSB-EP018321HU)
DNA polymerase theta suppresses mitotic crossing over
DNA polymerase θ up-regulation is associated with poor survival in ...
DNA Polymerase Theta Regulates the Growth and Development of Fusarium ...
Increased length of Ig gene conversion tracts in POLN−/−/POLQ−/− cells ...
Expression and Structural Analyses of Human DNA polymerase θ (POLQ) - PMC
Centrosome amplification in the lung cancer cells with concurrent ...
Template and primer requirements for DNA Pol θ-mediated end joining | PNAS
기초과학연구원
Structural basis for Polθ-helicase DNA binding and microhomology ...
Model for pol θ function in alt–EJ. Pol θ is drawn as a bipartite ...
Increased length of Ig gene conversion tracts in POLN / /POLQ ...
[보고서]인간 DNA 중합효소 Pol θ의 구조와 기능의 연관관계 분석 및 이를 이용한 항암제 발굴 기술 개발